Ari Robinson

Ari holds a Ph. D degree in Neurobiology from the Tel-Aviv university. His Ph. D thesis was in the field of cellular biology and focused on mitochondrial regulation by the Alzheimer’s disease associated protein Presenilin 1 (PS1). Before Ari joined IMBM, he was working for biotechnology start-up company (Delphar biopharma) in the fields of drug discovery and as a researcher at the Joseph Sagol Neuroscience Center (JSNC) at Sheba hospital. Ari joined IMBM in 2020 and he manages the three projects that IMBM is currently working on, in the field of Prostate cancer, Melanoma and Covid-19.

 

Scientific activity in 2023

Ari will focus on the analysis of colon cancer tumor dynamics from 3 different clinical trials datasets. In addition, Ari will incorporate and analyze 2 real-world datasets of advanced melanoma patients from Germany and Australia for the analysis of histopathological type influence on the overall survival of the patients, in the era of immunotherapy. 

 

  1. Publications

      1. Kogan Y, Robinson A, Itelman E, Bar-Nur Y, Jakobson DJ, Segal G, et al. Developing and validating a machine learning prognostic model for alerting to imminent deterioration of hospitalized patients with COVID-19. Sci Rep (2022) 12(1):19220
      2. Katsel P., Fam P., Tan W., Khan S., Gama-Sosa M., De-Gasperi R., Roussos P., Robinson A., Cooper I., Schnaider-Beeri M., Haroutunian V.Engagement of Vascular Early Response Genes Typifies Mild Cognitive Impairment. Alzheimer’s & Dementia. 2021;1–13.

      3. Noa Tejman-Yarden., Ari Robinson., Yaakov Davidov., Alexander Varvak., Fernando Reyes., Galia Rahav., Israel Nissan. (2019) Delftibactin-A, a Non Ribosomal Peptide with Broad Antimicrobial Activity. Frontiers in microbiology. 2019 Oct;10 (2377)

      4. Ari Robinson*., Irit Lubitz*., Dana Atrakchi-Baranes., Avital Licht-Murava., Pavel Katsel., Derek Leroith., Sigal Liraz-Zaltsman., Vahram Haroutunian., Michal Schnaider Beeri. (2019) Combination of insulin with a GLP1 agonist is associated with better memory and normal expression of insulin receptor pathway genes in a mouse model of Alzheimer’s Disease. J Mol Neurosci. 2019 Apr;67(4):504-510.

      5. Lezana JP, Dagan SY, Robinson A, Goldstein RS, Fainzilber M, Bronfman FC, Bronfman M. (2016) Axonal PPARγ promotes neuronal regeneration after injury. Dev Neurobiol. Jun; 76(6):688-701.

      6. Robinson A., Grosgen S., Mett J.,Zimmer V.C., Haupenthal V.J., Hundsdorfer B., Stahlmann C., Slobodskoy Y., Muller U.C, Hartmann T., Stein R. and Grimm M.O.W. (2014) Upregulation of PGC-1α expression by Alzheimer’s disease associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP. Aging Cell. Apr; 13(2):263-72.

      7. Robinson A., Kloog Y., Stein R., Assaf Y. (2010) Motor deficits and neurofibromatosis type 1 (NF1) -associated MRI impairments in mouse model of NF1. NMR Biomed. 23(10): 1173-1180.

      8. Fuchs E., Ayali A., Robinson A., Hulata E., Ben Jacob E. (2007) Co-emergence of regularity and complexity during neural network development. Dev. Neurobiol. 67(13): 1802-1814.

      9. Ayali A., Fuchs E., Zilberstein Y., Robinson A., Shefi O., Hulata E., Baruchi I., Ben-Jacob E. (2004) Contextual regularity and complexity of neuronal activity: from stand-alone cultures to task-performing animals. Complexity.9(6): 25-32.