Marat Spector holds a Ph. D degree in Physics from the Ben Gurion University of the Negev, Beer Sheva. His Ph. D thesis was in the field of ultrafast dynamics of charge carriers in laser heated metals and focused on temporal and spatial dependence of optical properties of metals subjected to modification due to an interaction of metallic subsystem with ultrafast optical pulses. Marat joined IMBM in February 2021 and, at present, he takes part in the Hormone Sensitive Prostate Cancer (HSPC) project..
Scientific activity in 2021
During this year, Marat’s research in the Prostate Cancer (PCa) project, focused on the development of a mathematical model that will predict the time to biochemical failure, that is, time to the emergence of resistance to androgen deprivation therapy (ADT) in patients subjected to hormonal therapy. Analysis of various trends that characterize the temporal dynamics of Prostate Specific Antigen (PSA) allowed us to suggest a possible mathematical model for predicting the personal PSA response to drug treatment.
Scientific activity in 2022
This year, Marat’s research will continue to be focused on HSPC. The mathematical model for HSPC will be adjusted and expanded, to include the effects of drug resistance and the Gleason Score factor which may influence the temporal dynamics of the measured PSA values. The model will be validated by new clinical results and will be used in the clinic to predict the time to failure of a specific patient subjected to hormonal treatment.
Spector M., Derevyanko S. (2020) Transient Temperature induced Plasmonic Crystal. Phys Rev B 102 (17), 174308.
I. Gurvich ., Spector M (equal contribution). (2020) The Thermal Lens Effect on Laser heating of a metal nano-sphere particle immersed in oil, J Quant. Spectr. Rad. Trans 252, 107066.